examining the role of neurons and their substructures in disease and disorders, as well as the pharmacological treatments used to address them.

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examining the role of neurons and their substructures in disease and disorders, as well as the pharmacological treatments used to address them.

In this unit, you have learned about neurons, glia, and their substructures. In this
assignment forum, you will examine the role of neurons and their substructures in
disease, disorders, and pharmacological treatments. For example, in Alzheimer’s
Disease, cytoskeletal microtubules break apart, and the tau proteins that once held
them together clump to form neurofibrillary tangles. Similarly, accumulation of misfolded
proteins is a characteristic of other neurological diseases such as Chronic Traumatic
Encephalopathy, Parkinson’s Disease, and Dementias.
Instructions:
Choose one of the following:
• Multiple Sclerosis
• Chronic Traumatic Encephalopathy
• Parkinson’s Disease
• Dementia
Define your chosen disease and briefly describe:
• The main symptoms associated with the disease.
• How neurons and their substructures are affected in these diseases.
• The role of glia in these diseases.
• The role of misfolded protein accumulation in the disease (If applicable).
Find a scholarly article on the neurobiology of either Alzheimer’s Disease, Multiple
Sclerosis, Chronic Traumatic Encephalopathy, Parkinson’s Disease or Dementia.
• Share at least two main takeaways from the article with your classmates.
• Provide a link to the article for your classmates and instructor to review.
Pharmacological Treatments:
Drugs used to treat a variety of neurological diseases and psychological disorders exert
their effects by affecting neurotransmitters and their receptors. For example, drug
treatments prevent the enzymatic degradation of acetylcholine in the synapse, which
ultimately may improve cognition.
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Choose one of the following:
• Depression
• Anxiety
• Schizophrenia
• Parkinson’s Disease
• ADHD
Describe how drugs used to treat these disorders exert their effects on neurotransmitter
levels and receptors.
• Support your response with a scholarly article.
• Share at least two main takeaways from the articles with your classmates.
• Provide a link to the article for your classmates and instructor to review.
Requirements:
• By the Friday deadline, share your presentation with the class in this Unit 3
Assignment Forum.
• By the Sunday deadline, review your classmates’ work and provide at least one
(1) reply

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